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Reasonable estimation shall be based on knowledge of the performance of the method and on measurement scope and shall make use of, for example, previous experience and validation data (section 5.4.6.2).

Upon discovering that synchrone should actually be asymptote, you could use the Find and Replace feature to replace all the plain, italic, and bold versions of the synchrone text simultaneously.

(2001) suggest that high doses of glucose in the culture medium may compete with glucosamine for transporter molecules that facilitate glucose entry into the chondrocytes and thus in ate the doses needed for these in vitro effects compared with the in vivo situation Clinical trials of the ef cacy of glucosamine began more than twenty years ago McAlindon et al (2000) carried out a meta-analysis of trials of glucosamine and chondroitin for the treatment of osteoarthritis of the hip and knee that were of more than four weeks duration and that had been published before mid-1999 The initial analysis of all eligible studies suggested a moderate to large bene cial effect of both of these substances in the treatment of osteoarthritis However, they found that there was a high likelihood of publication bias: negative ndings being less likely to have been published than positive ndings.

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One issue that developers struggle with when architecting Struts-based applications is the framework s inherent decoupling of type conversion and validation When the framework receives a form submission, it invokes generic reflection functionality in the BeanUtils package (formerly part of the Struts codebase and now a subproject of the Jakarta Commons project) to bind the form values in the request to the associated ActionForm The BeanUtils code is capable of converting string values to most common Java types (for example, Integer, BigDecimal, etc) and is able to map nested and indexed properties (for example address[0]city would be mapped to a property named city in the first element of an array of JavaBeans contained in an ActionForm property named address ) These capabilities make it theoretically possible to place a graph of value objects directly in an ActionForm.

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Some studies had small sample sizes and there were also quality issues with some of the studies The magnitude of the bene cial effects decreased when only the larger and higher quality studies were used for the analysis Many of the studies were funded by companies involved in the sale and manufacture of these supplements Despite these aws in the studies reviewed, they concluded that both compounds probably did have some ef cacy in the treatment of osteoarthritis although less than the crude aggregated data suggested The analysis also suggested that periods in excess of a month may be required to get full ef cacy Since this review by McAlindon et al, several large and long-term controlled studies of glucosamine use have been published Reginster et al (2001) carried out a three-year double-blind, placebo-controlled trial using a daily dose of 1500 mg of glucosamine.

(The Struts TagLib also avails itself of BeanUtils functionality, allowing properties to be mapped from the object graph into JSP tags during rendering) If an exception is thrown during conversion of any of the inbound form values as would happen, for example, if alphabetic characters were submitted in a form field bound to an Integer Struts aborts processing of the request, returning control to the JSP The result is that the user s input is lost, and no error message is provided Only if type conversion of all submitted form values succeeds is validation performed (when the framework calls the ActionForm s validate() method) While there are sufficient hooks in the Struts framework to allow an ambitious developer to alter the default inbound binding behavior to provide for more flexible error handling, no such hooks exist for modifying the outbound (that is, TagLib) binding behavior.